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Phosphodiesterase-4 inhibitors for asthma and chronic obstructive pulmonary disease.

Accurate prediction of dose-dependency of Theophylline metabolism in patients a priori is not possible, but patients with very high initial clearance rates (i.

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In this review we reassess the role of theophylline in the pharmacotherapy of asthma and specifically address three pivotal questions: What are the data justifying its continued use?

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Aspirin in combination with caffeine and ephedrine has failed to acutely increase the thermic effect of food.

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Drugs that may increase ethosuximide levels include isoniazid, ritonavir, and valproic acid.

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Your doctor might need to test your each time the dose is changed.

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Controlling asthma symptoms may decrease time lost from work or school.

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Terbutaline is considered the drug of choice in the United States, although intravenous albuterol and other β2-agonists are also available elsewhere.

Theophylline affects the cardiovascular (CV), central nervous (CN), gastrointestinal (GI), pulmonary, musculoskeletal, and metabolic systems.

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Antibiotics are probably helpful only in acute exacerbations of chronic bronchitis.

After multiple doses of theophylline, steady-state is reached in 30 to 65 hours (average 40 hours) in adults.

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Clients with peripheral vascular disease also usually have a certain amount of pain especially when the oxygen demand becomes greater than oxygen supply, such as with walking or exercising.

The lack of a reliable early marker for articular damage in pediatric patients and the uncertain causal relationship between the use of the newer fluoroquinolones (as opposed to nalidixic acid) may further complicate the question of risk-benefit.

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Its benefits come indirectly from that strength increase, and directly during recovery, which is why you also want to take creatine post-workout.

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Allergy skin tests may help diagnose allergic asthma, although they are not recommended for people with year-round asthma.

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